RESEARCH INTERESTS

Mammalian reproductive physiology; fertilization; development; and cryobiology.

GRANT SUPPORT

Protocols for Maturing and Freezing Monkey Oocytes, National Institutes of Health (C.A. VandeVoort, Principal Investigator, S.P. Leibo, Co-Investigator. Total Budget:  $2,878,26

SELECTED PUBLICATIONS

• Leibo SP.  2008  Cryopreservation of oocytes and embryos: Optimization by theoretical versus empirical analysis.   Theriogenology 69:37-47.
• Mazur P, Leibo SP, Seidel GE, Jr.  2008  Cryopreservation of the germplasm of animals used in biological and medical research: importance, impact, status, and future directions.   Biology of Reproduction  78:2-12.
• Leibo SP.  2007  Origins of techniques in human and animal embryology.   Theriogenology  67:2-5.
• Leibo SP, Kubisch HM, Schramm RD, Harrison RM, VandeVoort CA.  2007  Male-to-male differences in post-thaw motility of rhesus spermatozoa after cryopreservation of replicate ejaculates.   Journal of Medical Primatology 36:151-163.
• VandeVoort CA, Shirley CR, Hill DL, Leibo SP.  2007  Effects of cryoprotectants and cryopreservation on germinal vesicle-stage cumulus-oocyte complexes of rhesus monkeys.   Fertility and Sterility  doi:10.1016/j.fertnstert. 2007.06.105.
• Kardak A, Leibo SP, Devireddy RV.  2007  Membrane transport properties of equine and macaque ovarian tissues frozen in mixtures of dimethylsulfoxide and ethylene glycol.   Journal of Biomechanical Engineering 129:688-694.
• Devireddy RV, Amorim CA, Leibo SP.  2006  Permeability characteristics of ovine primordial follicles calculated with two parameter Kedem-Katchalsky formulation.  Cell Preservation Technology 4:188-198.
• Devireddy RV, Li G, Leibo SP.  2006  Suprazero cooling conditions significantly influence subzero permeability parameters of mammalian ovarian tissue. Molecular Reproduction and Development 73:330-341.
  
• VandeVoort CA, Leibo SP.  2005  Effect of cooling and exposure to ethylene glycol on in vitro maturation and embryo development of rhesus oocytes.   Cryo‑Letters 26:305‑312.
  
• Kuwayama M, Vajta G, Kato O, Leibo SP.  2005 Highly efficient vitrification method for cryopreservation of humans oocytes.   Reproductive Biomedicine Online 11:300‑308.
  
• Leibo SP. 2004  Cryopreservation of mammalian oocytes.  In  Preservation of Fertility. T. Tolandi, R. Gosden  (eds.)  Taylor and Francis, London UK. Pp 141‑155.
  
• Leibo SP.  2004  The early history of gamete cryobiology.  In  Life in the Frozen State.  BJ Fuller, N Lane, EE Benson (eds.)  CRC Press, Boca Raton, FL.  Pp 347‑370.